“I appreciate it when I come across a good organization and enjoy seeing people with passion for what they do!”
Auditor on behalf of large pharma
Puresyn has been delivering high quality products with personal service for over 30 years. Let’s get started.
Capacity at every stage.
Solutions for every project.
Puresyn offers the right grade of plasmid DNA for every stage of cell and gene therapy development. From early-stage research all the way through to commercialization, there is a quality Puresyn option that’s right for your work — including full GMP production.
Ready for any development need
State-of-the-art plasmid DNA manufacturing
- Convenient, cost-efficient replacement for performing in-house purification kits
- Available at two scales — Maxi and Mega — for up to 4mg of plasmid DNA
- Large-scale, highly pure plasmid DNA
- Utilizes our proprietary PolyFlo® resin (DMF 13090)
- Three levels of guaranteed specification available, with customizable options
- Produced to your final product specifications in our ISO Certified cleanroom facility
- Designed to ensure compliance with fundamental cGMP principles and Puresyn SOPs
- Highest level of plasmid DNA manufacturing and regulatory compliance
- For late-phase clinical and commercialization for critical starting materials and Phase I API requirements
Additional services to drive quality control and compliance
- Production optimization evaluation
- Cell bank characterization
- Sequencing
- Mycoplasma testing
- Sterility testing and storage
- Stability testing and storage
Confidence is built in
Puresyn started with the creation of our proprietary PolyFlo® resin over 30 years ago and has since earned a reputation for providing high-quality plasmid DNA with an exceptional level of personal service and attention. We have never wavered from these values, and they continue to guide us as we work side-by-side with our collaborators in their quest for the next breakthrough.
PolyFlo®: A resin like no other
Our proprietary PolyFlo® resin is the foundation of Puresyn’s exceptional purification control.
One quality system.
High production standards.
The Puresyn quality system ensures that plasmid DNA products meet or exceed our established specifications and those of our collaborators.
Puresyn clients expect our QA experts to go the extra mile. We’re always ready.
Our Pennsylvania headquarters boasts roughly 24,000 sq. ft. of manufacturing — that’s 70% of the entire space.
Puresyn’s ISO Certified cleanroom facility is fully compliant with cGMP plasmid DNA production, including environmental control to prevent cross-contamination.
We take your plasmid DNA personally.
Puresyn is not a one-size-fits-all kind of facility.
We’re an understand-every-aspect-of-your-needs kind of partner.
Hear from some of our collaborators
“Thank you for the services, we appreciate the timelines Puresyn has been able to maintain!”
Senior Manufacturing Manager, Clinical Stage Cell Therapy Company
“Puresyn is one of our favorite vendors to work with and always has been. Puresyn is always so responsive and communicative. Everyone in our lab thinks Puresyn is great.”
Director, Translational Research Operations, Academic Research Institution
“Just a quick note to thank the Puresyn team for the regular and well-documented weekly updates for our plasmid project. Also very much appreciate the flexibility in working with us to get a cell bank sample shipped to our External Contract Testing Lab.”
External Manufacturing Procurement, Clinical Stage Cell Therapy Company
“I hope that we can work together sometime in the future, as Puresyn has been an excellent partner.”
Director, R&D Project and Program Management, Cell Therapy Company
“I recommended Puresyn for our company RFI. I have really enjoyed working with Puresyn for our products and let my new organization’s supply Team know how well this has worked for us in the past.”
Associate Director Viral Vectors, Pharmaceutical
“I can absolutely confirm that Puresyn plasmid was used in EVERY batch of lentiviral vector that was used to dose EVERY patient in the phase 1 and registration studies.”
VP Operations, Pharmaceutical
“I want to say that it has been a real pleasure working with a local company like Puresyn. I will always appreciate how you saved us when we were in a pinch earlier this year. Personally, I plan to stay in the area, so perhaps we will work together again.”
Research Scientist, Targeted oncology company