We take your plasmid personally

By the time your starting material is in our hands, you will know your quality assurance expert and customer service partner by name. Over the past three decades that we have built our reputation of quality and excellence, we could have shifted to an impersonal fast-track approach, but that simply doesn’t align with what we know is important — partnership. We believe in standing by your side, being an extension of your team, and providing confidence at every stage of your work so you can be BreakthroughReadyTM.

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You’re more than a customer.
We consider you a collaborator.

For over three decades, Puresyn has intentionally taken a partner approach to the work we do with our collaborators. That means we:

Stand side-by-side with you.

We collaborate to understand the unique needs of your work, share consultant-level insight and advice, and provide high-quality plasmid DNA services.

Work as an extension of your team.

From the very first phone call, what matters most to you matters most to us.

Value a long-term working relationship.

Whether it’s the first time you reach out to us or you’ve been collaborating with Puresyn for years, we treat you and your work with utmost care and attention.

Show up for you, every time.

When you call, we respond immediately. No waiting around. No leaving messages in a voicemail void. When you need us, you can count on us to be there at every point along the way.

Keep you updated.

We provide regular reports and updates, so you’re always on top of our progress — with full transparency on your plasmid.

Ready to discuss how we can support your next project?

Our executive leadership

Long-term commitment starts at the top. Our leadership team has roughly 100 years of experience in plasmid DNA manufacturing right here at Puresyn. Always accessible and easy to work with, their vision and dedication shape everything we do.

Leslie Flynn

Vice President & General Manager
Leslie Flynn

Leslie started at Puresyn as an Office Manager in 1992. Over the years she worked her way to VP and General Manager. She is responsible for Administration, Human Resources, Legal, Finance, Equipment, Facilities and anything else that needs attention. 

​Dana Rosencrance​ Vice President, Quality & Operations Manager​

Dana Rosencrance

Vice President, Quality & Operations Manager
Dana Rosencrance

Dana started her career with Puresyn in 1998 as a Purification Scientist. Over the years, she has worked in both Quality Control and Quality Assurance. Currently, Dana is responsible for Quality and Operations and oversees the INDReady® Program. Dana takes the lead in customer onboarding, the quoting process and scheduling — as well as communication before, during and after each production. Additionally, Dana hosts and responds to Collaborator Audits and aids in HR and Business Development. 

​Michael Moxley​ Director, Business & ​Process Development

Michael Moxley

Director, Business & Process Development
Michael Moxley

Trained as a Fermentation Scientist, Mike began his career with Puresyn in 1998 performing viral purification and characterization. After working in plasmid purification for 11 years, he became Manager of the Fermentation Department. In his current role as Director of Business & Process Development, Mike’s main function is to align company efforts with guidance and regulatory compliance and help our collaborators do the same. He also assists in Puresyn’s marketing efforts.

Denise Ortlip

Director, Production
Denise Ortlip

Denise joined Puresyn in 2004 as a Purification Scientist before making her way into Production. Ultimately, she became Production Manager and then Production Director. Denise is responsible for all day-to-day production, operations, scheduling and troubleshooting.

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Collaboration is our pride and joy

Throughout Puresyn’s 30+ years of development work, collaboration has always mattered the most to us. We’re proud that our efforts support the academic, government, biotech and pharmaceutical communities — and make a daily difference to collaborators like you.

Ready to contribute to important cell and gene therapy research and help advance new lifesaving treatments?

“Your team is amazing! Thank you so much for everything you have done for these programs.”

 

Miguel Sena-Esteves, Ph.D.
Associate Professor, Department of Neurology
UMass Chan Medical School
Horae Gene Therapy Center
Director, Translational Institute for Molecular Therapeutics

Our story

Mid 1980s

John A. Thompson, Ph.D. discovers a unique polymer technology for separating and purifying nucleic acids and other biological molecules.

1992

Dr. Thompson licenses his technology, now known as PolyFlo® resin, to the newly founded Puresyn, Inc.

1997

The National Institutes of Health awards Puresyn $2.5 million in funding to develop a purification process that is reproducible and scalable.

2002

First INDReady® (specials program) performed by Puresyn

2002

Grant received: Phase I – Approved Recombinant Adenovirus Purification

2002

Grant received: Phase I, Phase II – Improved Adeno Associated Virus Purification

2003

Grant received: Phase I, Phase II – Improved Supercoil Plasma Purification

2004

FDA-approved cGMP study performed with vector constructed using INDReady® plasmid DNA

2010

First TransfectionReady plasmid DNA produced

2021

INDReady® facility opens in May – ISO Certified

2025

Puresyn expands to cGMP plasmid DNA production

Hear from some of our collaborators