Lentivirus vector plasmids
Third-generation Lentivirus (LV) manufacturing is achieved via quadruple transfection of a VSVG, Gagpol, Rev, and a transgene.
LV packaging plasmids
| Name | Source | Function |
|---|---|---|
| SNX-VSVG PL1034 | Syenex, Inc. | 3rd gen LV packaging plasmid containing the VSVG and kanamycin genes |
| SNX-Gagpol PL1035 | Syenex, Inc. | 3rd gen LV packaging plasmid containing the Gag, Pol, and kanamycin genes |
| SNX-Rev PL1036 | Syenex, Inc. | 3rd gen LV packaging plasmid containing the Rev and kanamycin genes |
SNX-VSVG PL1034
Owner: Syenex, Inc. SNX-VSVG is a LV plasmid containing the VSVG and Kanamycin genes. SNX-VSVG was developed and owned by Syenex, Inc. and is designed to be used in conjunction with the LV packaging plasmids to manufacture an LV vector.
SNX-Gagpol PL1035
Owner: Syenex, Inc. SNX- Gagpol is an LV plasmid containing the Gag, Pol, and Kanamycin genes. SNX- Gagpol was developed and owned by Syenex, Inc. and is designed to be used in conjunction with the LV packaging plasmids to manufacture an LV vector.
SNX-Rev PL1036
Owner: Syenex, Inc. SNX- Rev is an LV plasmid containing the Rev and Kanamycin genes. SNX- Rev was developed and owned by Syenex, Inc. and is designed to be used in conjunction with the LV packaging plasmids to manufacture an LV vector.
| Scale | Specification | Cost per mg |
|---|---|---|
| 1-90 mg | ResearchReady | $70 |
| 100-240 mg | ResearchReady | $65 |
| 250-490 mg | ResearchReady | $35 |
| ≥500 mg | ResearchReady | $25 |
| 50-240 mg | INDReady® | $500 |
| 250-490 mg | INDReady® | $270 |
| ≥500 mg | INDReady® | $210 |
Custom scales: Available
Terms of purchase: See Below
Commonly purchased with: LV Packaging plasmid
Why are packaging plasmids crucial?
Production of Viral Particles: Packaging plasmids enable the host cells (often HEK293T cells) to produce the structural and enzymatic components necessary to assemble viral particles that can encapsulate and deliver the engineered genetic material.
Regulation of Viral Assembly: Packaging plasmids allow for the control of viral titer and transfection efficiency by adjusting the ratio and strength of the plasmids used in production.
Off-the-shelf packaging plasmids
Cell and gene therapy programs face multiple challenges with coordinating resources, lengthy production timelines, and associated costs.
To alleviate some of those challenges, Puresyn offers the following packaging plasmids to help facilitate your research:
Royalty free
SNX-VSVG PL1034
SNX-Gagpol PL1035
SNX-Rev PL1036
Our packaging plasmids are available under the following conditions:
ResearchReady plasmid DNA
Our large-scale ResearchReady services utilize our proprietary PolyFlo® resin (DMF 13090), resulting in highly pure DNA meeting the agreed-upon specifications. ResearchReady plasmid DNA supports the Research & Development phase across a variety of applications.
INDReady® plasmid DNA
As your work moves to early-phase clinical trials, our quality system ensures your plasmid DNA is manufactured in compliance with fundamental GMP principles and Puresyn SOPs. You can be confident that the final product specifications have been met and the DNA product is of the highest quality and suitable for use in GMP production.
All Orders for Packaging Plasmid are subject to the following Terms and Conditions:
- Orders are accepted effective as of the earlier of (i) a date provided in a notice from Puresyn, Inc. (“Puresyn”) or (ii) the date Puresyn commences fulfillment. Order acceptance is not guaranteed and may be conditioned by subsequent notice.
- Payment terms: Net 30 plus interest at 1.5% per month on undisputed receivables over 30 days.
- Confidentiality. All materials, data, documentation (including without limitation Puresyn Manufacturing Summaries) disclosed or deliverable in connection with Orders are the Confidential Information of the respective parties, subject to confidentiality and use restrictions in effect. In the absence thereof, each party shall respect and observe the reasonable ownership and confidentiality interests of the other party in its Confidential Information.
- Ownership: Collaborator may use Packaging Plasmid in combination with Collaborator-provided plasmid for viral vector production and may retain ownership of resulting product, including technology, know-how, information and data derived therefrom. Except as so stipulated, nothing herein shall be construed to convey any right, title or interest in or to Packaging Plasmid.
- Puresyn disclaims all warranties, express or implied, of merchantability, fitness for a particular purpose or title.
- Puresyn is not liable for consequential, special or punitive damages.
- Puresyn rejects provisions in any Collaborator pre-printed, standard, posted or “click-through” forms that are inconsistent herewith.
[REV: 9OCT2025]